I also don't think just creating a centrifugal force is the right way to duplicate an earth like environment, you also need a magnetic field like the earth's ---
If you have to produce 1g (or 1/3g or 1/6g) there are three ways: spin the sucker, add mass or sprinkle some skiffy pixie dust and cast a magic gravity spell, like they do in almost all SF shows and movies.
At my previous job, my boss studied the inner ear and how it affected balance. We had chairs and swings that could move/rotate people at very high accelerations to see how large angular accelerations affected the inner ear and the eyes.
I asked him a few times about rotating spacecraft and he didn't think it would be difficult to adapt except at the extremes of small size/high g.
For magnetic fields, that's also not a show stopper. Run a current through coils (which could function as a means of propulsion if designed right) add some polyethylene and water shielding and that should greatly reduce the effects of charged particles and most cosmic rays.
If we hadn't wasted 30 years on the Shuttle/ISS we might have had a space wheel by now.